Interaction of Bacteriophage l with Its E. coli Receptor, LamB
نویسندگان
چکیده
منابع مشابه
Interaction of Bacteriophage λ with Its E. coli Receptor, LamB
The initial step of viral infection is the binding of a virus onto the host cell surface. This first viral-host interaction would determine subsequent infection steps and the fate of the entire infection process. A basic understating of the underlining mechanism of initial virus-host binding is a prerequisite for establishing the nature of viral infection. Bacteriophage λ and its host Esch...
متن کاملNew insights into pb5, the receptor binding protein of bacteriophage T5, and its interaction with its Escherichia coli receptor FhuA.
The majority of bacterial viruses are bacteriophages bearing a tail that serves to recognise the bacterial surface and deliver the genome into the host cell. Infection is initiated by the irreversible interaction between the viral receptor binding protein (RBP) and a receptor at the surface of the bacterium. This interaction results ultimately in the phage DNA release in the host cytoplasm. Pha...
متن کاملThe protein interaction network of bacteriophage lambda with its host, Escherichia coli.
Although most of the 73 open reading frames (ORFs) in bacteriophage λ have been investigated intensively, the function of many genes in host-phage interactions remains poorly understood. Using yeast two-hybrid screens of all lambda ORFs for interactions with its host Escherichia coli, we determined a raw data set of 631 host-phage interactions resulting in a set of 62 high-confidence interactio...
متن کاملStructural Basis of the Interaction of the Pyelonephritic E. coli Adhesin to Its Human Kidney Receptor
PapG is the adhesin at the tip of the P pilus that mediates attachment of uropathogenic Escherichia coli to the uroepithelium of the human kidney. The human specific allele of PapG binds to globoside (GbO4), which consists of the tetrasaccharide GalNAc beta 1-3Gal alpha 1-4Gal beta 1-4Glc linked to ceramide. Here, we present the crystal structures of a binary complex of the PapG receptor bindin...
متن کاملBacteriophage-specific proteins in e. Coli infected with an RNA bacteriophage.
The f2 group of RNA coliphages (f2, MS2, R17, fr), first isolated by Loeb and Zinder,' are closely related, small viruses with single-stranded RNA of about one million molecular weight (for a review of RNA phages, see ref. 2). The number of proteins encoded in the viral RNA is therefore small. To date, two phage-specified proteins have been identified chemically or enzymatically in infected cel...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Viruses
سال: 2012
ISSN: 1999-4915
DOI: 10.3390/v4113162